In traditional medicine Thymus serpyllum L. (wild thyme) herb represents a part of a large number of herbal medicinal formulations such as syrups, tinctures, infusions, teas, and decoctions. In recent years, there has been a growing interest in testing the biological properties of wild thyme, because the plant is a high-quality raw material, rich in essential oil and pharmacologically active polyphenolic compounds, which can be included in various formulations in the pharmaceutical, cosmetic, food, and chemical industries. Wild thyme extracts and essential oil have shown significant nitric oxide, ABTS and DPPH radicals scavenging potential, ferrous ion chelating property, reducing activity and ability to inhibit peroxidation of deoxyribonucleic acid (DNA), proteins and lipids. Wild thyme extracts exerted antibacterial activity against Bacillus cereus, Enterococcus faecalis, Listeria monocytogenes, Staphylococcus aureus, Escherichia coli, Salmonella enterica, Yersinia enterocolitica, as well as Lactic acid bacteria. Wild thyme essential oil has shown antibacterial potential against E. coli, L. monocytogenes, P. aeruginosa, S. enteritidis, S. aureus, Streptococcus salivariu, S. mutans, S. sanguinis, S. pyogenes, E. feacalis, B. cereus, B. subtilis, B. pumilis, Lactobacillus acidophilus, Proteus mirabilis, Klebsiella pneumoniae, Salmonella choleraesuis, and Salmonella poona. T. serpyllum extract possesses antifungal activity against Fusarium solani, F. moniliforme, Aspergillus flavus, Microsporum canis, Alternaria species, Candida albicans, and C. glabarata. The essential oil efficiently inhibited the growth of C. albicans, C. glabrata and Aspergillus fungi. Depending on the concentration, wild thyme extract significantly relaxed spontaneous contractions, as well as acetylcholine-, potassium chloride-, barium chlorideand calcium chloride-induced contractions of the isolated rat ileum. The extract significantly reduced the expression of the inducible enzyme cyclooxygenase-2 and inhibited acetylcholinesterase, myeloperoxidase and α-glucosidase activity. T. serpyllum extract has shown cytotoxic activity on human breast cancer cell lines, while essential oil has shown the antitumor potential in human cell lung cancer, colon, cervical, hepatocellular, prostate, and breast adeno-carcinoma.
Adams, M., Schneider, S.-V., Kluge, M., Kessler, M., & Hamburger, M. (2012). Epilepsy in the Renaissance: A survey of remedies from 16th and 17th century German herbals. Journal of Ethnopharmacology, 143(1), 1–13. https://doi.org/10.1016/j.jep.2012.06.010
Ait M’Barek, L., Ait Mouse, H., Jaâfari, A., Aboufatima, R., Benharref, A., Kamal, M., Bénard, J., El Abbadi, N., Bensalah, M., Gamouh, A., Chait, A., Dalal, A., & Zyad, A. (2007). Cytotoxic effect of essential oil of thyme (Thymus broussonettii) on the IGR-OV1 tumor cells resistant to chemotherapy. Brazilian Journal of Medical and Biological Research, 40(11), 1537–1544. https://doi.org/10.1590/s0100-879x2007001100014
Alamgeer, A. (n.d.). Hypoglycemic and hematological effects of aqueous extract of Thymus serpyllum Linn. in alloxan-induced diabetic rabbits. African Journal of Pharmacy and Pharmacology, 6(40), 2845–2850. https://doi.org/10.5897/ajpp12.1343
Al-Fatimi, M., Wurster, M., & Schröder, G. (n.d.). & Lindequist, U.(2010). In vitro antimicrobial, cytotoxic and radical scav-enging activities and chemical constituents of the endemicthymus.
Algieri, F., Rodriguez-Nogales, A., Garrido-Mesa, N., Zorrilla, P., Burkard, N., Pischel, I., Sievers, H., Benedek, B., Feistel, B., Walbroel, B., Rodriguez-Cabezas, M. E., & Galvez, J. (2014). Intestinal anti-inflammatory activity of the Serpylli herba extract in experimental models of rodent colitis. Journal of Crohn’s and Colitis, 8(8), 775–788. https://doi.org/10.1016/j.crohns.2013.12.012
Amorati, R., Foti, M. C., & Valgimigli, L. (2013). Antioxidant Activity of Essential Oils. Journal of Agricultural and Food Chemistry, 61(46), 10835–10847. https://doi.org/10.1021/jf403496k
Aralbaeva, A. N., Mamataeva, A. T., Zhaparkulova, N. I., Utegalieva, R. S., Khanin, M., Danilenko, M., & Murzakhmetova, M. K. (2017). A composition of medicinal plants with an enhanced ability to suppress microsomal lipid peroxidation and a protective activity against carbon tetrachloride-induced hepatotoxicity. Biomedicine & Pharmacotherapy, 96, 1283–1291. https://doi.org/10.1016/j.biopha.2017.11.085
Aziz, S. (2008). Studies on the chemical constituents ofthymus serpyllum.Turkish Journal of Chemistry,32(5),605–614.
Berdowska, I., Zieliński, B., Fecka, I., Kulbacka, J., Saczko, J., & Gamian, A. (2013). Cytotoxic impact of pheno-lics from lamiaceae species on human breast cancer cells.Food Chemistry,141(2 (pp. 1313–1321). https://doi.org/10.1016/j.foodchem.2013.03.090doi:10.1016/j.foodchem.2013.03.090
Boros, B., Jakabová, S., Dörnyei, Á., Horváth, G., Pluhár, Z., Kilár, F., & Felinger, A. (2010). Determination of polyphenolic compounds by liquid chromatography–mass spectrometry in Thymus species. Journal of Chromatography A, 1217(51), 7972–7980. https://doi.org/10.1016/j.chroma.2010.07.042
Bozkurt, E., Atmaca, H., Kisim, A., Uzunoglu, S., Uslu, R., & Karaca, B. (2012). Effects ofThymus serpyllumExtract on Cell Proliferation, Apoptosis and Epigenetic Events in Human Breast Cancer Cells. Nutrition and Cancer, 64(8), 1245–1250. https://doi.org/10.1080/01635581.2012.719658
Brankovic, S., Kitic, D., Radenkovic, M., Veljkovic, S., Jankovic, T., Savikin, K., & Zdunic, G. (2011). Spasmolytic Activity of the Ethanol Extract of Sideritis raeseri spp. raeseri Boiss. & Heldr. on the Isolated Rat Ileum Contractions. Journal of Medicinal Food, 14(5), 495–498. https://doi.org/10.1089/jmf.2010.0036
Čančarević, A., Bugarski, B., Šavikin, K., & Zdunić, G. (2013). activity and ethnomedicinal use of thymus vul-garis and thymus serpyllum.Lekovite sirovine(33 (pp. 3–17).
Costa, D. C., Costa, H. S., Albuquerque, T. G., Ramos, F., Castilho, M. C., & Sanches-Silva, A. (2015). Advances in phenolic compounds analysis of aromatic plants and their potential applications. Trends in Food Science & Technology, 45(2), 336–354. https://doi.org/10.1016/j.tifs.2015.06.009
Dussossoy, E., Bichon, F., Bony, E., Portet, K., Brat, P., Vaillant, F., & Poucheret, P. (2016). Pulmonary anti-inflammatoryeffects and spasmolytic properties of costa rican noni juice( morinda citrifolia l.).Journal of Ethnopharmacology,192 (p. 264).
Engelbertz, J., Lechtenberg, M., Studt, L., Hensel, A., & Verspohl, E. J. (2012). Bioassay-guided fractionation of a thymol-deprived hydrophilic thyme extract and its antispasmodic effect. Journal of Ethnopharmacology, 141(3), 848–853. https://doi.org/10.1016/j.jep.2012.03.025
Ertas, A., Boga, M., Yilmaz, M. A., Yesil, Y., Tel, G., Temel, H., Hasimi, N., Gazioglu, I., Ozturk, M., & Ugurlu, P. (2015). A detailed study on the chemical and biological profiles of essential oil and methanol extract of Thymus nummularius (Anzer tea): Rosmarinic acid. Industrial Crops and Products, 67, 336–345. https://doi.org/10.1016/j.indcrop.2015.01.064
Fayad, N., AL-Obaidi, O. H. S., Al-Noor, T. H., & Ezzat, M. (2013). Water and alcohol extraction of thyme plant (thy-mus vulgaris) and activity study against bacteria, tumorsand used as anti-oxidant in margarine manufacture.In-novative Systems Design and Engineering,4(1 (pp. 41–51).
Fresco, P., Borges, F., Marques, M., & Diniz, C. (2010). The Anticancer Properties of Dietary Polyphenols and its Relation with Apoptosis. Current Pharmaceutical Design, 16(1), 114–134. https://doi.org/10.2174/138161210789941856
Gairola, S., Sharma, J., & Bedi, Y. S. (2014). A cross-cultural analysis of Jammu, Kashmir and Ladakh (India) medicinal plant use. Journal of Ethnopharmacology, 155(2), 925–986. https://doi.org/10.1016/j.jep.2014.06.029
Galati, G., & O’Brien, P. J. (2004). Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radical Biology and Medicine, 37(3), 287–303. https://doi.org/10.1016/j.freeradbiomed.2004.04.034
Gholamhoseinian, A., Fallah, H., Sharifi-far, F., & Mirtajaddini, M. (n.d.). The Inhibitory Effect of Some Iranian Plants Extracts on the Alpha Glucosidase. Iranian Journal of Basic Medical Sciences, 11(1). https://doi.org/10.22038/ijbms.2008.5190
Heber, D. (2004). for herbal medicines.
Hosseinzadeh, S., Jafarikukhdan, A., Hosseini, A., & Armand, R. (2015). The Application of Medicinal Plants in Traditional and Modern Medicine: A Review of <i>Thymus vulgaris</i> International Journal of Clinical Medicine, 06(09), 635–642. https://doi.org/10.4236/ijcm.2015.69084
Hussain, A. I., Anwar, F., Chatha, S. A. S., Latif, S., Sherazi, S. T. H., Ahmad, A., Worthington, J., & Sarker, S. D. (2013). Chemical composition and bioactivity studies of the essential oils from two Thymus species from the Pakistani flora. LWT - Food Science and Technology, 50(1), 185–192. https://doi.org/10.1016/j.lwt.2012.06.003
Jovanka, L., Ivana, C., Goran, T., Sava, P., Slavica, S., Tamara, C.-G., & Ljiljana, K. (2011). In vitro antibacterial activityof essential oils from plant family lamiaceae.Rom (Issue Lett,16(2), pp. 6034–6041).
Jovanović, A. A., Balanč, B. D., Petrović, P., Pravilović, R., & Djordjević, V. B. (n.d.). Pharmacological potential of Thymus serpyllum L. (wild thyme) extracts and essential oil: A review. JOURNAL OF ENGINEERING & PROCESSING MANAGEMENT, 13(2). https://doi.org/10.7251/jepm2102032j
Jovanović, A. A., Đorđević, V. B., Zdunić, G. M., Pljevljakušić, D. S., Šavikin, K. P., Gođevac, D. M., & Bugarski, B. M. (2017). Optimization of the extraction process of polyphenols from Thymus serpyllum L. herb using maceration, heat- and ultrasound-assisted techniques. Separation and Purification Technology, 179, 369–380. https://doi.org/10.1016/j.seppur.2017.01.055
Jovanović, A. A., Petrović, P. M., Zdunić, G. M., Šavikin, K. P., Kitić, D., Đorđević, V. B., Bugarski, B. M., & Branković, S. (2021). Influence of lyophilized Thymus serpyllum L. extracts on the gastrointestinal system: Spasmolytic, antimicrobial and antioxidant properties. South African Journal of Botany, 142, 274–283. https://doi.org/10.1016/j.sajb.2021.06.028
Jovanović, A., Djordjević, V., Petrović, P., Pljevljakušić, D., Zdunić, G., Šavikin, K., & Bugarski, B. (2021). The in-fluence of different extraction conditions on polyphenolcontent. Antioxidant and Antimicrobial Activities of Wildthyme.Journal of Applied Research on Medicinal and Aro-Matic Plants,25, 10032.
Jovanovic, A., Djordjevic, V., Zdunic, G., Savikin, K., Pljevljakusic, D., & Bugarski, B. (2016). Ultrasound-assisted extraction of polyphenols from Thymus serpyllum and its antioxidant activity. Chemical Industry, 70(4), 391–398. https://doi.org/10.2298/hemind150629044j
Jovanović, A., Skrt, M., Petrović, P., Častvan, I., Zdunić, G., Šavikin, K., & Bugarski, B. (2019). Ethanol Thymus serpyllum extracts: Evaluation of extraction conditions via total polyphenol content and radical scavenging activity. Lekovite Sirovine, 39, 23–29. https://doi.org/10.5937/leksir1939023j
Jurinjak Tušek, A., Benković, M., Valinger, D., Jurina, T., Belščak-Cvitanović, A., & Gajdoš Kljusurić, J. (2018). Optimizing bioactive compounds extraction from different medicinal plants and prediction through nonlinear and linear models. Industrial Crops and Products, 126, 449–458. https://doi.org/10.1016/j.indcrop.2018.10.040
Juturu, V. (2014). Polyphenols and Cardiometabolic Syndrome. In Polyphenols in Human Health and Disease (pp. 1067–1076). https://doi.org/10.1016/b978-0-12-398456-2.00082-7
Kačániová, M., Terentjeva, M., Vukovic, N., Puchalski, C., Roychoudhury, S., Kunová, S., Klūga, A., Tokár, M., Kluz, M., & Ivanišová, E. (2017). The antioxidant and antimicrobial activity of essential oils against Pseudomonas spp. isolated from fish. Saudi Pharmaceutical Journal, 25(8), 1108–1116. https://doi.org/10.1016/j.jsps.2017.07.005
Kayani, S., Ahmad, M., Zafar, M., Sultana, S., Khan, M. P. Z., Ashraf, M. A., Hussain, J., & Yaseen, G. (2014). Ethnobotanical uses of medicinal plants for respiratory disorders among the inhabitants of Gallies – Abbottabad, Northern Pakistan. Journal of Ethnopharmacology, 156, 47–60. https://doi.org/10.1016/j.jep.2014.08.005
Kindl, M., Blažeković, B., Bucar, F., & Vladimir-Knežević, S. (2015). Antioxidant and Anticholinesterase Potential of SixThymusSpecies. Evidence-Based Complementary and Alternative Medicine, 2015, 1–10. https://doi.org/10.1155/2015/403950
Komes, D., Belščak-Cvitanović, A., Horžić, D., Rusak, G., Likić, S., & Berendika, M. (2011). Phenolic composition and antioxidant properties of some traditionally used medicinal plants affected by the extraction time and hydrolysis. Phytochemical Analysis, 22(2), 172–180. https://doi.org/10.1002/pca.1264
Kovačević, N. (2004). Srpska školskaknjiga.
Kozuharova, E. (n.d.). Descriptive study of contemporary status of the traditional knowledge on medicinal plants in Bulgaria. African Journal of Pharmacy and Pharmacology, 7(5), 185–198. https://doi.org/10.5897/ajpp12.871
Kulišić, T., Kriško, A., Dragović-Uzelac, V., Miloš, M., & Pifat, G. (2007). The effects of essential oils and aqueous tea infusions of oregano (Origanum vulgareL. spp.hirtum), thyme (Thymus vulgarisL.) and wild thyme (Thymus serpyllumL.) on the copper-induced oxidation of human low-density lipoproteins. International Journal of Food Sciences and Nutrition, 58(2), 87–93. https://doi.org/10.1080/09637480601108307
Kulisic, T., Radonic, A., & Milos, M. (2005). Antioxidant proper-ties of thyme (thymus vulgaris l.) and wild thyme (thymusserpyllum l. Essential Oils.Italian Journal of Food, science,17(3, 315.
Lee, C.-J., Chen, L.-G., Chang, T.-L., Ke, W.-M., Lo, Y.-F., & Wang, C.-C. (2011). The correlation between skin-care effects and phytochemical contents in Lamiaceae plants. Food Chemistry, 124(3), 833–841. https://doi.org/10.1016/j.foodchem.2010.07.003
Mannan, A., Inayatullah, S., Akhtar, M. Z., Qayyum, M., & Mirza, B. (2009). Biological evaluation of wild thyme (Thymus serpyllum). Pharmaceutical Biology, 47(7), 628–633. https://doi.org/10.1080/13880200902915622
Mata, A. T., Proença, C., Ferreira, A. R., Serralheiro, M. L. M., Nogueira, J. M. F., & Araújo, M. E. M. (2007). Antioxidant and antiacetylcholinesterase activities of five plants used as Portuguese food spices. Food Chemistry, 103(3), 778–786. https://doi.org/10.1016/j.foodchem.2006.09.017
Mati, E., & de Boer, H. (2011). Ethnobotany and trade of medicinal plants in the Qaysari Market, Kurdish Autonomous Region, Iraq. Journal of Ethnopharmacology, 133(2), 490–510. https://doi.org/10.1016/j.jep.2010.10.023
Melzig, M. F., Pertz, H. H., & Krenn, L. (2001). Anti-inflammatory and spasmolytic activity of extracts from Droserae Herba. Phytomedicine, 8(3), 225–229. https://doi.org/10.1078/0944-7113-00031
Mihailovic-Stanojevic, N., Belščak-Cvitanović, A., Grujić-Milanović, J., Ivanov, M., Jovović, Dj., Bugarski, D., & Miloradović, Z. (2013). Antioxidant and Antihypertensive Activity of Extract from Thymus serpyllum L. in Experimental Hypertension. Plant Foods for Human Nutrition, 68(3), 235–240. https://doi.org/10.1007/s11130-013-0368-7
Miron, T. L., Plaza, M., Bahrim, G., Ibáñez, E., & Herrero, M. (2011). Chemical composition of bioactive pressurized extracts of Romanian aromatic plants. Journal of Chromatography A, 1218(30), 4918–4927. https://doi.org/10.1016/j.chroma.2010.11.055
Monographs, E. (2003).
Mrkonjić, Ž., Rakić, D., Olgun, E. O., Canli, O., Kaplan, M., Teslić, N., Zeković, Z., & Pavlić, B. (2021). Optimization of antioxidants recovery from wild thyme (Thymus serpyllum L.) by ultrasound-assisted extraction: Multi-response approach. Journal of Applied Research on Medicinal and Aromatic Plants, 24, 100333. https://doi.org/10.1016/j.jarmap.2021.100333
Mustafa, B., Hajdari, A., Pieroni, A., Pulaj, B., Koro, X., & Quave, C. L. (2015). A cross-cultural comparison of folk plant uses among Albanians, Bosniaks, Gorani and Turks living in south Kosovo. Journal of Ethnobiology and Ethnomedicine, 11(1). https://doi.org/10.1186/s13002-015-0023-5
Nedorostova, L., Kloucek, P., Kokoska, L., Stolcova, M., & Pulkrabek, J. (2009). Antimicrobial properties of selected essential oils in vapour phase against foodborne bacteria. Food Control, 20(2), 157–160. https://doi.org/10.1016/j.foodcont.2008.03.007
Neergheen, V. S., Bahorun, T., Taylor, E. W., Jen, L.-S., & Aruoma, O. I. (2010). Targeting specific cell signaling transduction pathways by dietary and medicinal phytochemicals in cancer chemoprevention. Toxicology, 278(2), 229–241. https://doi.org/10.1016/j.tox.2009.10.010
Nikolić, M., Glamočlija, J., Ferreira, I. C. F. R., Calhelha, R. C., Fernandes, Â., Marković, T., Marković, D., Giweli, A., & Soković, M. (2014). Chemical composition, antimicrobial, antioxidant and antitumor activity of Thymus serpyllum L., Thymus algeriensis Boiss. and Reut and Thymus vulgaris L. essential oils. Industrial Crops and Products, 52, 183–190. https://doi.org/10.1016/j.indcrop.2013.10.006
Ningappa, M. B., Dinesha, R., & Srinivas, L. (2008). Antioxidant and free radical scavenging activities of polyphenol-enriched curry leaf (Murraya koenigii L.) extracts. Food Chemistry, 106(2), 720–728. https://doi.org/10.1016/j.foodchem.2007.06.057
Oalđe, M. M., Kolarević, S. M., Živković, J. C., Vuković-Gačić, B. S., Jovanović Marić, J. M., Kračun Kolarević, M. J., Đorđević, J. Z., Alimpić Aradski, A. Z., Marin, P. D., Šavikin, K. P., & Duletić-Laušević, S. N. (2020). The impact of different extracts of six Lamiaceae species on deleterious effects of oxidative stress assessed in acellular, prokaryotic and eukaryotic models in vitro. Saudi Pharmaceutical Journal, 28(12), 1592–1604. https://doi.org/10.1016/j.jsps.2020.10.006
Oszagyán, M., Simándi, B., Sawinsky, J., & Kéry, Á. (1996). A Comparison Between the Oil and Supercritical Carbon Dioxide Extract of Hungarian Wild Thyme(Thymus serpyllumL.). Journal of Essential Oil Research, 8(3), 333–335. https://doi.org/10.1080/10412905.1996.9700629
Ouedrhiri, W., Balouiri, M., Bouhdid, S., Moja, S., Chahdi, F. O., Taleb, M., & Greche, H. (2016). Mixture design of Origanum compactum, Origanum majorana and Thymus serpyllum essential oils: Optimization of their antibacterial effect. Industrial Crops and Products, 89, 1–9. https://doi.org/10.1016/j.indcrop.2016.04.049
Parejo, I., Viladomat, F., Bastida, J., Rosas-Romero, A., Flerlage, N., Burillo, J., & Codina, C. (2002). Comparison between the Radical Scavenging Activity and Antioxidant Activity of Six Distilled and Nondistilled Mediterranean Herbs and Aromatic Plants. Journal of Agricultural and Food Chemistry, 50(23), 6882–6890. https://doi.org/10.1021/jf020540a
Pavel, M., & Alecu, F. (2008). Antifungal activity of thy-mus serpyllum essential oil against candida albicans andcandida non-albicans clinical isolates. In In18th europeancongress of clinical microbiology and infectious diseases (ec-cmid.Bucharest.
Petrovic, S., Ristic, M., Petrovic, N., Lazic, M., Franciskovic, M., & Petrovic, S. (2014). Chemical composition and antioxidative activity of essential oil of Thymus serpyllum L. Chemical Industry, 68(3), 389–397. https://doi.org/10.2298/hemind130513051p
Pioro-Jabrucka, E., Suchorska-Tropilo, K., & Rzewuska. (2007). Antibacterial activity of the essential oil of com-mon thyme [thymus pulegioides l.] and wild thyme [thy-mus serpyllum l.].Herba Polonica,3(53.
Raal, A., Paaver, U., Arak, E., & Orav, A. (2004). Contentand composition of the essential oil of thymus serpyllum l.growing wild in estonia.Medicina: Vol. Kaunas),40(8 (pp. 795–800).
Rang, H., Dale, M., Ritter, J., & Moore, P. (2005).
Rasooli, I., & Mirmostafa, S. A. (2002). Antibacterial properties of Thymus pubescens and Thymus serpyllum essential oils. Fitoterapia, 73(3), 244–250. https://doi.org/10.1016/s0367-326x(02)00064-3
Roby, M. H. H., Sarhan, M. A., Selim, K. A.-H., & Khalel, K. I. (2013). Evaluation of antioxidant activity, total phenols and phenolic compounds in thyme (Thymus vulgaris L.), sage (Salvia officinalis L.), and marjoram (Origanum majorana L.) extracts. Industrial Crops and Products, 43, 827–831. https://doi.org/10.1016/j.indcrop.2012.08.029
Sen, S., & Chakraborty, R. (2011). The Role of Antioxidants in Human Health. In ACS Symposium Series (pp. 1–37). https://doi.org/10.1021/bk-2011-1083.ch001
Singh, J. P., Kaur, A., Singh, N., Nim, L., Shevkani, K., Kaur, H., & Arora, D. S. (2016). In vitro antioxidant and antimicrobial properties of jambolan (Syzygium cumini) fruit polyphenols. LWT - Food Science and Technology, 65, 1025–1030. https://doi.org/10.1016/j.lwt.2015.09.038
Šojić, B., Tomović, V., Kocić-Tanackov, S., Kovačević, D. B., Putnik, P., Mrkonjić, Ž., Đurović, S., Jokanović, M., Ivić, M., Škaljac, S., & Pavlić, B. (2020). Supercritical extracts of wild thyme (Thymus serpyllum L.) by-product as natural antioxidants in ground pork patties. LWT, 130, 109661. https://doi.org/10.1016/j.lwt.2020.109661
Stojanovic, R., Belscak-Cvitanovic, A., Manojlovic, V., Komes, D., Nedovic, V., & Bugarski, B. (2012). Encapsulation of thyme (Thymus serpyllum L.) aqueous extract in calcium alginate beads. Journal of the Science of Food and Agriculture, 92(3), 685–696. https://doi.org/10.1002/jsfa.4632
Teissedre, P. L., & Waterhouse, A. L. (2000). Inhibition of Oxidation of Human Low-Density Lipoproteins by Phenolic Substances in Different Essential Oils Varieties. Journal of Agricultural and Food Chemistry, 48(9), 3801–3805. https://doi.org/10.1021/jf990921x
Tepe, B., Daferera, D., Sökmen, M., Polissiou, M., & Sökmen, A. (2004). In Vitro Antimicrobial and Antioxidant Activities of the Essential Oils and Various Extracts of Thymus eigii M. Zohary et P.H. Davis. Journal of Agricultural and Food Chemistry, 52(5), 1132–1137. https://doi.org/10.1021/jf035094l
Tona, L., Kambu, K., Ngimbi, N., Mesia, K., Penge, O., Lusakibanza, M., Cimanga, K., De Bruyne, T., Apers, S., Totte, J., Pieters, L., & Vlietinck, A. J. (2000). Antiamoebic and spasmolytic activities of extracts from some antidiarrhoeal traditional preparations used in Kinshasa, Congo. Phytomedicine, 7(1), 31–38. https://doi.org/10.1016/s0944-7113(00)80019-7
Trifković, K. T., Milašinović, N. Z., Djordjević, V. B., Krušić, M. T. K., Knežević-Jugović, Z. D., Nedović, V. A., & Bugarski, B. M. (2014). Chitosan microbeads for encapsulation of thyme (Thymus serpyllum L.) polyphenols. Carbohydrate Polymers, 111, 901–907. https://doi.org/10.1016/j.carbpol.2014.05.053
(2010). Chemical composition andantioxidant and anti-listeria activities of essential oils ob-tained from some egyptian plants.Journal of Agricul-tural and Food Chemistry,58(16. https://doi.org/10.7251/JEPM2102032JOpen
Citation
Copyright
Authors retain copyright. This work is made freely available online under an open-access model under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC-http://creativecommons.org/licenses/by-nc-nd/4.0/BY-NC-ND 4.0).
Trace determination of nickel in Thymus serpyllum L. (wild thyme) tea with a matrix matching strategy by UV–Vis spectrometry after vortex-assisted DES/DPC-based microextraction
Chemical Composition and <i>In Vitro</i> Cytotoxicity of Endemic <i>Thymus brachychilus</i> Jalas Against Human Breast Adenocarcinoma (MCF-7, HTB-22), Human Lung Adenocarcinoma (A549, CRM-CCL-185), and Human Glioblastoma Cells (U-118 MG, HTB-15)
Živan Mrkonjić, Muammer Kaplan, Sanja Milošević, Danica Božović, Aleksandra Sknepnek, Dunja Miletić, Ivana Lazarević Mrkonjić, Dušan Rakić, Zoran Zeković, Branimir Pavlić
(2024)
Green Extraction Approach for Isolation of Bioactive Compounds in Wild Thyme (Thymus serpyllum L.) Herbal Dust—Chemical Profile, Antioxidant and Antimicrobial Activity and Comparison with Conventional Techniques
The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.
