Studying of lipophilicity of potential biological active cyanoacetamide derivatives
By applying the Lipinski’s rule for selected cyanoacetamide derivatives the possible existence of biological activity is theoretically investigated. Alos,using appropriate software packages and applying reverse-phase thin-layer chromatography (RP TLC18 F254s) in water-t-butanol, water-dimethylformamide and water-dimethylsulfoxide the lipophil...
By SUZANA APOSTOLOV, ĐENĐI VAŠTAG